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| Before the development of modern product safety standards, consumers
simply had to gamble on the safety of every thing. A few examples
serve as grim reminders of what life was like before products
and medical treatments were evaluated for safety prior to human
exposure. Early cures for tapeworm parasites caused blindness. Around the turn of the century, physicians treated syphilis patients with compounds that caused ner vous system complications and, sometimes, death. In the early 1930's, an untested eyelash dye was marketed, resulting in cases of blindness and at least one death. This tragedy and another unfortunate episode in which 107 people died as the result of taking an untested cough medicine led to the pas- sage of the Federal Food, Drug, and Cosmetic Act of 1938. This federal law mandated that drugs be tested for safety before they are marketed. In contrast, today many new compounds proposed for commercial or medical use never even reach the public marketplace because of safety problems identified by premarket testing. The pesticide 2-AAF (2-acetylamino fluorene) was thought to be a promising chemical for reducing crop loss and expanding agricultural production. Safety research, however, indicated that 2-AAF might be a potent carcinogen (cancer-causing chemical). As a result, the pesticide was not brought to market, and general human exposure was avoided. (next page) |
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